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1

Amyloid blood biomarker detects Alzheimer’s disease prior to clinical onset

Evin, Genevieve

Journal:

Journal of Laboratory and Precision Medicine

Year:

2018

Language:

english

File:

PDF, 161 KB

english, 2018

2

A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease

Victoria M. Perreau, Sandra Orchard, Paul A. Adlard, Shayne A. Bellingham, Roberto Cappai, Giuseppe D. Ciccotosto, Tiffany F. Cowie, Peter J. Crouch, James A. Duce, Genevieve Evin, Noel G. Faux, Andre

Journal:

PROTEOMICS - Clinical Applications

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

3

Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle

Nancy T. Ilaya, Geneviève Evin, Colin L. Masters, Janetta G. Culvenor

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 224 KB

english, 2004

4

P4-206: Identification of gamma-secretase activities with distinct pharmacological properties

Evin, Genevieve, Ho, Michael, Ilaya, Nancy T., Hoke, David E., Laughton, Katrina, Li, Qiao-Xin, Masters, Colin L., Culvenor, Janetta G.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 66 KB

english, 2008

5

Peptide Coupling Reagents; VIII. A High Yield Preparation of Phenyl Esters of Amino Acids using Benzotriazolyloxytris[dimethylamino]phosphonium Hexafluorophosphate (BOP Reagent)

CASTRO, Bertrand, EVIN, Geneviève, SELVE, Claude, SEYER, René

Journal:

Year:

1977

File:

PDF, 92 KB

1977

6

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

Janetta G. Culvenor, Nancy T. Ilaya, Michael T. Ryan, Louise Canterford, David E. Hoke, Nicholas A. Williamson, Catriona A. McLean, Colin L. Masters, Geneviève Evin

Journal:

Year:

2004

Language:

english

File:

PDF, 358 KB

english, 2004

7

P4-256 Nicastrin expression is not coordinated with presenilin level in mouse systemic tissues

Ilaya, Nancy T., Evin, Genevieve, Masters, Colin L., Culvenor, Janetta G.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

8

Selecting cells with different Alzheimer's disease γ-secretase activity using FACS : Differential effect of presenilin exon 9 deletion on γ- and ε-cleavage

M. Fleur Sernee, Geneviève Evin, Janetta G. Culvenor, José A. Villadangos, Konrad Beyreuther, Colin L. Masters, Roberto Cappai

Journal:

Year:

2003

Language:

english

File:

PDF, 325 KB

english, 2003

9

Modulation of amyloid precursor protein processing by synthetic ceramide analogues

Hongyun Li, Woojin S. Kim, Gilles J. Guillemin, Andrew F. Hill, Genevieve Evin, Brett Garner

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

10

P3-401

Evin, Genevieve, Ho, Michael, Ilaya, Nancy T., Hoke, David E., White, Anthony R., Masters, Colin L., Culvenor, Janetta G.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

11

Chemical approach of synthetic immunogens from human renin

Galen, François-X., Evin, Geneviéve, Carelli, Claude, Bouhnik, Jacob, Michel, Jean-B., Ferhentz, Jean-A., Le N'Guyen, Dung, Seyer, René, Carlson, William D., Castro, Bertrand

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1987

Language:

english

File:

PDF, 896 KB

english, 1987

12

Future Therapeutics in Alzheimer’s Disease: Development Status of BACE Inhibitors

Evin, Genevieve

Journal:

Year:

2016

Language:

english

File:

PDF, 915 KB

english, 2016

13

Increased β-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects

R. M. Damian Holsinger, Catriona A. McLean, Steven J. Collins, Colin L. Masters, Geneviève Evin

Journal:

Annals of Neurology

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

14

Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets

Geneviève Evin, Aiqin Zhu, R.M. Damian Holsinger, Colin L. Masters, Qiao-Xin Li

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

15

In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc

David E. Hoke, Jiang-Li Tan, Nancy T. Ilaya, Janetta G. Culvenor, Stephanie J. Smith, Anthony R. White, Colin L. Masters, Geneviève M. Evin

Journal:

Year:

2005

Language:

english

File:

PDF, 479 KB

english, 2005

16

Biogenesis and metabolism of Alzheimer’s disease Aβ amyloid peptides

Geneviève Evin, Andreas Weidemann

Journal:

Year:

2002

Language:

english

File:

PDF, 240 KB

english, 2002

17

Subcellular localization of the Alzheimer's disease amyloid precursor protein and derived polypeptides expressed in a recombinant yeast system

Culvenor, Janetta G., Henry, Anna, Hartmann, Tobias, Evin, Geneviève, Galatis, Denise, Friedhuber, Anna, Jayasena, U.L.H. Rajiv, Underwood, John R., Beyreuther, Konrad, Masters, Colin L., Cappai, Robe

Journal:

Year:

1998

Language:

english

File:

PDF, 3.28 MB

english, 1998

18

Effect of Metal Chelators on γ -Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate

Ho, Michael, Hoke, David E., Chua, Yee Jia, Li, Qiao-Xin, Culvenor, Janetta G., Masters, Colin, White, Anthony R., Evin, Geneviève

Journal:

International Journal of Alzheimer's Disease

Year:

2011

Language:

english

File:

PDF, 2.22 MB

english, 2011

19

Decreased expression of GGA3 Protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein

Claudia Santosa, Stefanie Rasche, Adel Barakat, Shayne A. Bellingham, Michael Ho, Jiangli Tan, Andrew F. Hill, Colin L. Masters, Catriona McLean, Geneviève Evin

Journal:

Neurobiology of Disease

Year:

2011

Language:

english

File:

PDF, 978 KB

english, 2011

20

Inhibition of γ-Secretase as a Therapeutic Intervention for Alzheimer’s Disease

Dr Geneviève Evin,Marijke Fleur Sernee,Colin L. Masters

Journal:

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

21

BACE Inhibitors as Potential Therapeutics for Alzheimers disease

Evin, Genevieve, Kenche, Vijaya

Journal:

Recent Patents on CNS Drug Discovery

Year:

2007

Language:

english

File:

PDF, 380 KB

english, 2007

22

A new genetic screening assay for gamma-secretase

M. Fleur Sernee, Genevieve M. Evin, Roberto Cappai

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 189 KB

english, 2000

23

Decreased Neuregulin 1 C-terminal fragment in Brodmann's area 6 of patients with schizophrenia

Adel Barakat, Brian Dean, Elizabeth Scarr, Geneviève Evin

Journal:

Schizophrenia Research

Year:

2010

Language:

english

File:

PDF, 656 KB

english, 2010

24

P4-292 Gamma-secretase inhibitors stabilize a 900 KDA presenilin complex: a tetrameric model for gamma-secretase

Evin, Genevieve, Canterford, Louise D., Hoke, David E., Holsinger, R.M. Damian, Culvenor, Janetta G., Masters, Colin L.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

25

P4-185 Analysis of bace protein and activity in human cerebrospinal fluid

Damian Holsinger, R.M., McLean, Catriona A., Masters, Colin L., Evin, Genevieve

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

26

Peptide Coupling Reagents VI 1 . A Novel, Cheaper Preparation of Benzotriazolyloxytris[dimethylamino]phosphonium Hexafluorophosphate (BOP Reagent)

CASTRO, Bertrand, DORMOY, Jean-Robert, DOURTOGLOU, Basile, EVIN, Geneviève, SELVE, Claude, ZIEGLER, Jean-Claude

Journal:

Year:

1976

File:

PDF, 107 KB

1976

27

Dissociation of ERK signalling inhibition from the anti-amyloidogenic action of synthetic ceramide analogues

Li, Hongyun, Evin, Genevieve, Hill, Andrew F., Hung, Ya Hui, Bush, Ashley I., Garner, Brett

Journal:

Clinical Science

Year:

2012

Language:

english

File:

PDF, 818 KB

english, 2012

28

A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease

Victoria M. Perreau, Sandra Orchard, Paul A. Adlard, Shayne A. Bellingham, Roberto Cappai, Giuseppe D. Ciccotosto, Tiffany F. Cowie, Peter J. Crouch, James A. Duce, Genevieve Evin, Noel G. Faux, Andre

Journal:

Year:

2010

Language:

english

File:

PDF, 555 KB

english, 2010

29

BACE: Therapeutic target and potential biomarker for Alzheimer's disease

Geneviève Evin, Adel Barakat, Colin L. Masters

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2010

Language:

english

File:

PDF, 356 KB

english, 2010

30

Alternative transcripts of presenilin-1 associated with frontotemporal dementia

Evin, Geneviève, Smith, Margaret J., Tziotis, Angela, McLean, Catriona, Canterford, Louise, Sharples, Robyn A., Cappai, Roberto, Weidemann, Andreas, Beyreuther, Konrad, Cotton, Richard G. H., Masters,

Journal:

Year:

2002

Language:

english

File:

PDF, 169 KB

english, 2002

31

A synthetic substrate assay for the gamma-secretase of the β-A4 amyloid of alzheimer's disease

Dr. Geneviève Evin, Konrad Beyreuther, Colin L. Masters

Journal:

Journal of Peptide Science

Year:

1995

Language:

english

File:

PDF, 600 KB

english, 1995

32

A crossreactive antipeptide monoclonal antibody with specificity for lysyl-lysine (J. Immunol. Methods 140 (1991) 249–258)

Levon M. Khachigian, Genevieve Evin, Francis J. Morgan, Dwain A. Owensby, Colin N. Chesterman

Journal:

Journal of Immunological Methods

Year:

1992

Language:

english

File:

PDF, 24 KB

english, 1992

33

Candidate .gamma.-Secretases in the Generation of the Carboxyl Terminus of the Alzheimer's Disease .beta.A4 Amyloid: Possible Involvement of Cathepsin D

Evin, Genevieve, Cappai, Roberto, Li, Qiao-Xin, Culvenor, Janetta G., Small, David H., Beyreuther, Konrad, Masters, Colin L.

Journal:

Year:

1995

Language:

english

File:

PDF, 2.79 MB

english, 1995

34

Altered Amyloid-β Metabolism and Deposition in Genomic-based β-Secretase Transgenic Mice

Chiocco, Matthew J., Kulnane, Laura Shapiro, Younkin, Linda, Younkin, Steve, Evin, Geneviève, Lamb, Bruce T.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 946 KB

english, 2004

35

Permafrost research sites in the Alps: Excursions of the international workshop on permafrost and periglacial environments in mountain areas

Wilfried Haeberli, Michèle Evin, Geneviève Tenthorey, H. R. Kensen, Martin Hoelzle, Felix Keller, Daniel Vonder Mühll, Stephan Wagner, Manuela Pelfini, Claudio Smiraglia

Journal:

Permafrost and Periglacial Processes

Year:

1992

Language:

english

File:

PDF, 3.08 MB

english, 1992

36

Transition-State Analogue γ-Secretase Inhibitors Stabilize a 900 kDa Presenilin/Nicastrin Complex †

Evin, Geneviève, Canterford, Louise D., Hoke, David E., Sharples, Robyn A., Culvenor, Janetta G., Masters, Colin L.

Journal:

Year:

2005

Language:

english

File:

PDF, 442 KB

english, 2005

37

BACE Inhibitors as Potential Drugs for the Treatment of Alzheimers Disease: Focus on Bioactivity

Evin, Genevieve, Lessene, Guillaume, Wilkins, Simon

Journal:

Recent Patents on CNS Drug Discovery

Year:

2011

Language:

english

File:

PDF, 297 KB

english, 2011

38

Critical analysis of the use of β-site amyloid precursor protein-cleaving enzyme 1 inhibitors in the treatment of Alzheimer's disease

Evin, Genevieve, Barakat, Adel

Journal:

Degenerative Neurological and Neuromuscular Disease

Year:

2014

Language:

english

File:

PDF, 461 KB

english, 2014

39

P3-345: Presenilin-1 interacts with acetylcholinesterase

Saez-Valero, Javier, Silveyra, María-Ximena, Evin, Geneviève, Montenegro, María-Fernanda, Vidal, Cecilo J., Martínez, Salvador, Culvenor, Janetta G.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 71 KB

english, 2008

40

The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from γ-secretase

Janelle Nunan, Mark S. Shearman, Frédéric Checler, Roberto Cappai, Geneviève Evin, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Year:

2001

Language:

english

File:

PDF, 602 KB

english, 2001

41

β-Site APP-cleaving enzyme 1 trafficking and Alzheimer’s disease pathogenesis

Jiangli Tan, Geneviève Evin

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 230 KB

english, 2012

42

BACE1 as a Therapeutic Target in Alzheimer’s Disease: Rationale and Current Status

Genevieve Evin, Christopher Hince

Journal:

Year:

2013

Language:

english

File:

PDF, 364 KB

english, 2013

43

Decreased expression of GGA1 and GGA3 adaptor proteins in Alzheimer's disease frontal cortex

Evin, Genevieve, Santosa, Claudia, Tan, Jiangli, Barakat, Adel, Masters, Colin L., McLean, Catriona

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

44

Processing of the Alzheimer's Disease Amyloid Precursor Protein in Pichia pastoris : Immunodetection of α-, β-, and γ-Secretase Products †

Le Brocque, Darren, Henry, Anna, Cappai, Roberto, Li, Qiao-Xin, Tanner, Jane E., Galatis, Denise, Gray, Carol, Holmes, Steven, Underwood, John R., Beyreuther, Konrad, Masters, Colin L., Evin, Genevièv

Journal:

Year:

1998

Language:

english

File:

PDF, 114 KB

english, 1998

45

Synthesis and Renin Inhibitory Properties of a New Soluble Pepstatin Derivative

Gardes, Joëlle, Evin, Geneviève, Castro, Bertrand, Corvol, Pierre, Menard, Joël

Journal:

Journal of Cardiovascular Pharmacology

Year:

1980

File:

PDF, 563 KB

1980

46

APP intracellular domain is increased and soluble Aβ is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease

Amee J George, R.M.Damian Holsinger, Catriona A McLean, Katrina M Laughton, Konrad Beyreuther, Genevieve Evin, Colin L Masters, Qiao-Xin Li

Journal:

Neurobiology of Disease

Year:

2004

Language:

english

File:

PDF, 385 KB

english, 2004

47

Subcellular distribution of presenilins, APP and Aβin lymphocytes from a kindred with a new PS1 delta-9 mutation

Genevieve M. Evin, Margaret J. Smith, Robyn A. Sharples, Janetta G. Culvenor

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

48

An alternative strategy for the radioimmunoassay of angiotensin peptides using amino-terminal-directed antisera: measurement of eight angiotensin peptides in human plasma

Lawrence, Anne C., Evin, Genevieve, Kladis, Athena, Campbell, Duncan J.

Journal:

Journal of Hypertension

Year:

1990

File:

PDF, 884 KB

1990

49

P2-025: Copper depletion by menkes ATP7A over-expression dramatically alters the metabolism of APP and APLP2 in cell culture

Michael A. Cater, Andrew Tsatsanis, Irene Volitakis, Qiao-Xin Li, Genevieve Evin, Julian F.B. Mercer, Colin L. Masters, Robert A. Cherny, Ashley I. Bush

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

50

A crossreactive antipeptide monoclonal antibody with specificity for lysyl-lysine

Levon M. Khachigian, Genevieve Evin, Francis J. Morgan, Dwain A. Owensby, Colin N. Chesterman

Journal:

Journal of Immunological Methods

Year:

1991

Language:

english

File:

PDF, 707 KB

english, 1991

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